Relationship Between Increasing Body Weight, Insulin Resistance, Inflammation, Adipocytokine Leptin, and Coronary Circulatory Function
نویسندگان
چکیده
منابع مشابه
Relationship between obesity, insulin resistance, and coronary heart disease risk.
OBJECTIVES The study goals were to: 1) define the relationship between body mass index (BMI) and insulin resistance in 314 nondiabetic, normotensive, healthy volunteers; and 2) determine the relationship between each of these two variables and coronary heart disease (CHD) risk factors. BACKGROUND The importance of obesity as a risk factor for type 2 diabetes and hypertension is well-recognize...
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Traditionally, nuts have been considered a staple food, but because of their high energy and fat content are not considered good for body weight control or insulin sensitivity. Frequent consumption of nuts reduces the risk of coronary artery disease and type-2 diabetes and nut-enriched diets favourably alter blood lipids in normal and hypercholesterolemic individuals under controlled and free-l...
متن کاملGhrelin and leptin levels in obese adolescents. Relationship with body fat and insulin resistance.
OBJECTIVE Ghrelin and leptin levels are influenced by body fat (BF%), pubertal stage and possibly insulin resistance (IR). The aim of our study was: 1) To compare fasting ghrelin and leptin levels between obese and non-obese, adolescents, 2) to investigate possible correlations of these hormones with BF %, as well as IR. DESIGN Twenty obese insulin resistant (IR) adolescents, twenty obese non...
متن کاملEffects of changes in body weight and insulin resistance on inflammation and endothelial function in morbid obesity after bariatric surgery.
Metabolic alterations such as insulin resistance are thought to underlie the endothelial dysfunction and low grade inflammation found in morbid obesity. Twenty-six morbidly obese patients, aged 39.0 +/- 10.0 (mean +/- sd), were evaluated before and 4.2 +/- 0.8 months after bariatric surgery. A marked increment in the insulin sensitivity index (S(I)) and the endothelium-dependent vasodilatory re...
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sion tomography/computed tomography study. Circulation 2008;117:1693–700. 25. CamiciPG,CreaF.Coronarymicrovasculardysfunction.NEngl JMed2007;356:830–40. 26. Knaapen P, Camici PG, Marques KM, Nijveldt R, Bax JJ, Westerhof N et al. Coronary microvascular resistance: methods for its quantification in humans. Basic Res Cardiol 2009;104:485–98. 27. Schindler TH, Cardenas J, Prior JO, Facta AD, Kreis...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2006
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2005.10.062